Manned orbital launches in 2000
Launches:
| Date | Site | Rocket | Mission | Crew | Launch outcome |
|---|---|---|---|---|---|
| 2000-02-11 | Cape Canaveral | Space Shuttle | Endeavour F14 | 6 | success |
| 2000-04-04 | Baikonur | Soyuz-U 11A511U | Soyuz TM-30 | 2 | success |
| 2000-05-19 | Cape Canaveral | Space Shuttle | Atlantis F21 | 7 | success |
| 2000-09-08 | Cape Canaveral | Space Shuttle | Atlantis F22 | 7 | success |
| 2000-10-11 | Cape Canaveral | Space Shuttle | Discovery F28 / ITS-Z1 / PMA 3 | 7 | success |
| 2000-10-31 | Baikonur | Soyuz-U 11A511U | Soyuz TM-31 | 3 | success |
| 2000-12-01 | Cape Canaveral | Space Shuttle | Endeavour F15 / ITS-P6 | 5 | success |