Manned orbital launches in 1991
Launches:
| Date | Site | Rocket | Mission | Crew | Launch outcome |
|---|---|---|---|---|---|
| 1991-04-05 | Cape Canaveral | Space Shuttle | Atlantis F8 / CGRO (Compton) | 5 | success |
| 1991-04-28 | Cape Canaveral | Space Shuttle | Discovery F12 / IBSS-SPAS / CRO A / CRO B / CRO C | 7 | success |
| 1991-05-18 | Baikonur | Soyuz-U2 11A511U2 | Soyuz TM-12 | 3 | success |
| 1991-06-05 | Cape Canaveral | Space Shuttle | Columbia F11 | 7 | success |
| 1991-08-02 | Cape Canaveral | Space Shuttle | Atlantis F9 / TDRS 5 [IUS] | 5 | success |
| 1991-09-12 | Cape Canaveral | Space Shuttle | Discovery F13 / UARS | 5 | success |
| 1991-10-02 | Baikonur | Soyuz-U2 11A511U2 | Soyuz TM-13 | 3 | success |
| 1991-11-24 | Cape Canaveral | Space Shuttle | Atlantis F10 / DSP 16 (USA 75) [IUS] | 6 | success |